Disease caused - causes, forms, treatment
- 29 Jul 01:45
- Disease Of The Skin
Disease-induced ( chronic follicular dyskeratosis) is a hereditary skin disease that manifests itself as a brown or brown colored rash. Nodules are associated with hair follicles, they have a conical surface and are covered with densecrust.
- 1 Causes of
- 2 disease development Clinical manifestations
- 3 Forms of the disease
- 4 Methods of diagnosis
- 5 Treatment of
- 5.1 Treatment of folk healers methods
- 6 Prevention and prognosis
- 7 Photo
Causes of the disease
The main causes of the disease Darina is genetically transmittedpredisposition. The presence of a defective gene leads to insufficient absorption of vitamin A, as well as due to the absence of some enzymes, there is a violation of the processes of keratinization of the skin. The kink killing is typical for such diseases as the usual ichthyosis, ichthyosis.
If a parent has a defective gene, then with the probability of 50% of the child developing follicular dyskeratosis. However, due to a generation, the disease is not transmitted, if a healthy baby appears on the sick parents, then his offspring do not threaten Daryna's illness.
Follicular dyskeratosis is not contagious, it is not transmitted when in contact with the patient.
Clinical manifestations of
Darya's disease manifests itself as the appearance of follicular and perifollicular flat nodules( papules).The size of the nodes varies within 1-3 mm, and sometimes larger nodes appear. Most papules with follicular dyskeratosis are covered with hard, dry horny crust of dirty brown color. A chisel is slightly raised above the surface of healthy skin, but holds firmly on the surface of the papule. When removing the crust, you can observe a deepening of the skin in the form of funnel.
Nodes are most often formed in the mouths of hair follicles - follicles, which can sometimes lead to the development of such a disease as folliculitis. Rashes with Darya's disease, as a rule, are symmetrically located and capture rather large areas of the skin. The most likely sites of localization are large skin folds, bending surfaces of the joints, in the area of the collarbones, on the scalp, between the shoulder blades, in the nasolabial folds. Sometimes follicular dyskeratosis rash covers almost the whole body.
Dina's rash on the head may be milial( conical) papules with a flat surface, as well as wart plaques with a very loose surface. After removing the crust, headaches may appear on the head of baldness, which is one of the main symptoms of follicular dyskeratosis.
With the progression of the disease, Darini appears all the new rash, with the old rash merging with the formation of large areas of defeat.
In large folds of the skin under follicular dyskeratosis large tumors can appear that resemble the color of inflorescence of cauliflower. Such formations may form bubbles, erosion and cracks. Papules, which, when the disease of Darina covers the back of the brush, often resemble flat warts.
When follicular dyskeratosis is often affected by the nails, there are longitudinal strips, cracks, sometimes there is hyperkeratosis of the leg buds. Mucus in this disease is rarely affected, however, sometimes papules can be formed on the mucous membranes of the mouth, or even of the esophagus.
Forms of the disease
In dermatology there are several forms of Darya's disease.
- The localized form of follicular dyskeratosis is characterized by a linear arrangement of foci, rash covers only limited areas of the skin.
- For isolated forms of follicular dyskeratosis, the appearance on the skin of not only typical nodules, but also warlike enlargements is characteristic.
- The vesicle-bullous variety of the disease is found somewhat less frequently, with the disease along with papules there are bubbles on the skin.
In some cases, with Daryni's disease, there are systemic pathologies, including: mental retardation, eye diseases, abnormalities of the skeleton, epilepsy, mental disorders, dysfunction of the endocrine systems.
Diagnosis of Darya's disease is based on the evaluation of a clinical picture and the collection of anamnesis of the disease and family history. Histopathological study of skin biopsy is prescribed for correct diagnosis. Differentiate Dina's disease from:
- Red Flat Lice;
- Epidermis dislocation vernacular;
- Seborrheic dermatitis;
- Cyrle Diseases;
Dina's disease usually cures outpatient treatment. However, in the case of a sharp aggravation of the process or in the event that the defeat covers large areas of the skin, hospitalization may be offered to the dermatological hospital.
Treatment for follicular dyskeratosis is prescribed symptomatic. It is prescribed to receive an oil solution of vitamin A orally or in the form of intramuscular injections. The dose of vitamin preparation is adjusted according to age. The course of vitamins is up to 3 months, then make a break, equal in time, and then restore the reception.
Positive result in follicular dyskyratosis gives treatment with retinoids, as well as taking vitamins of groups E and B12.With Darya's disease, spa treatment, moderate ultraviolet irradiation is shown.
A good effect in follicular dyskeratosis is given by pearl baths( a kind of hydromassage) in combination with applications of keratolytic or corticosteroid ointments with the addition of vitamin A.
In the presence of large increases in the disease Daryni shows the removal of neoplasms by surgical methods or electrocoagulation.
If the disease is complicated by a bacterial infection, which is manifested by pyoderma( impetigo, gangrenous pyoderma), antibiotics are prescribed. With a hormonal imbalance corrective therapy is selected.
Treatment by methods of folk healers
In case of Daniyna disease, treatment with medicinal herbs can be used simultaneously with medication therapy.
Folk medicine for follicular dyskeratosis is recommended:
Prophylaxis and Forecast
Since Daryini's disease is inherited, as a primary prevention, genetic counseling before pregnancy can be recommended if there are cases of follicular dyskeratosis in the family.
Prognosis for life with Dinaine's disease is favorable, often long remission is observed, and often remission occurs not as a result of therapy, but with age. However, complete recovery in Darya's illness usually does not occur.