Paniculitis - Causes, Symptoms, Diagnosis, Treatment, Photo
- 14 Jun 12:45
- Disease Of The Skin
Paniculitis or granuloma fat is a disease that results in necrotic changes in subcutaneous fatty tissue. The disease is prone to recurrence.
As a result of the inflammatory process during panniculitis, the fat cells are destroyed and replaced by the binding tissue ofby the formation of infiltration of plaques or nodes.
The most dangerous is the visceral form of panniculitis, which affects the adipose tissue of the internal organs - the kidneys, pancreas, liver, etc.
- 1 Causes of the disease
- 2 Classification of the forms of the disease
- 3 Clinical picture
- 3.1 Primary( idiopathic) form
- 3.2 BlyashkovaForm
- 3.3 Nodular form
- 3.4 Infiltrative form
- 3.5 Visceral form
- 4 Diagnostic methods
- 5 Treatment scheme
- 6 Treatment by folk methods
- 7 Forecast and prevention of
- 8 Photo
Approximately half of patients with fat granuloma develops spontaneously, that is, against the background of relative health. This form is more common in women of reproductive age, and is called idiopathic.
In the remaining 50% of patients with panniculitis, inflammation of adipose tissue develops as one of the symptoms of a systemic disease - sarcoidosis, red lupus erythematosus, and others.
Causes of panniculitis may be due to immune disorders, colds, and reactions to some medications.
Doctors believe that the basis of the development of fatty granuloma is the pathological change in metabolic processes in fatty tissues. However, despite many years of research and study of panniculitis, until now, it was not possible to get a clear idea of the mechanism of development of the inflammatory process.
Classification of the forms of the disease
In dermatology, the primary and secondary form of fat granuloma are isolated.
In the first case, paniculitis develops without the influence of any factors, that is for unknown reasons. This form is called Weber-Chrischen syndrome and is most commonly found among women under 40 who are overweight.
Secondary paniculitis occurs for a variety of reasons, which allowed the development of a system for classifying forms of the disease.
Allocate the following forms of Paniculite.
- Immunological paniculitis. The disease develops against the background of the systemic vasculitis. Sometimes this variant of fatty granuloma appears in children as a form of the course of bundled erythema.
- A paniculum fermentative. The development of inflammation is associated with the action of enzymes produced by the pancreas. As a rule, it manifests itself against a background of pancreatitis.
- Polymerative cellular granuloma develops in patients with lymphoma, histiocytosis, leukemia, and the like.
- Lupus paniculitis is one of the manifestations of red lupus ripening in acute form.
- A cold paniculitis develops as a local reaction to overcooling. It manifests itself as the emergence of dense nodes, which themselves pass through a few weeks.
- Crystalline paniculitis is a consequence of gout or renal failure. It develops through deposits in subcutaneous fat of urates and calcifications.
- Artificial fat granuloma develops at the injection site after administration of various drugs.
- The steroidal form of panniculitis often develops in children as a response to steroid therapy. No special treatment is required, the inflammation runs independently after discontinuation of the medication.
- The hereditary form of panniculitis develops due to the deficiency of a certain substance - A1-antipryspina.
In addition, there is a classification of forms of panniculitis depending on the type of skin lesions. Allocate the plaque, nodal and infiltrative form of fat granuloma.
Clinical picture of
Paniculitis may occur in an acute, recurrent or subacute form.
The symptomatic pattern of panniculitis depends on the shape.
Primary( idiopathic) form of
The main symptoms of spontaneous( primary) fat granuloma are the appearance of nodes located in the subcutaneous fatty tissue. The nodes can be located at different depths. In most cases, nodes appear on the legs or hands, less often - on the abdomen, chest or face. After the destruction of the site in its place there are areas of atrophy of adipose tissue, which looks like skin depression.
In some cases, in patients with the appearance of nodes, there is a symptom characteristic of the flu - weakness, muscle pain, headache, etc.
Pancreatic paniculitis manifests itself in the formation of multiple nodes that grow rapidly enough to form large conglomerates. In severe cases, the conglomerate extends over the entire area of the subcutaneous tissue of the affected area - shoulder, thigh, legs. In this case, the compression causes compression of the vascular and nerve bundles, causing edema. Lymphostasis may subsequently develop due to a lymph outflow.
At node nodes, nodes with a diameter of 3 to 50 mm are formed. The skin over the nodes acquires a red or burgundy shade. The nodules for fusion in this variant of disease development are not sloping.
In this variant of panniculite, melting of formed conglomerates occurs with the formation of fluctuations. Outwardly, the defeat looks like a phlegmon or abscess. The difference is that when the nodes are open, no manure is observed. Separated from the site is a yellowish oil of oily consistency. After the node is open, a ulcer is formed in its place, which does not heal for a long time.
This variant of panniculitis is characterized by defeat of the adipose tissue of the internal organs. Such patients develop pancreatitis, hepatitis, nephritis, retroviral tissue, and characteristic nodes may be formed.
Diagnosis of panniculitis is based on the study of clinical picture and analysis. The patient should be sent for examination to specialists - nephrologist, gastroenterologist, rheumatologist.
The patient will need to donate blood to biochemistry, liver tests, to conduct a study of enzymes produced by the pancreas. As a rule, ultrasound examination of internal organs is intended.
Blood testing for sterility is performed to exclude septic lesions. A biopsy of the site is performed to determine the exact diagnosis.
Treatment Scheme for
Treatment for panniculitis is tailored individually, depending on the course and form of the disease. Treatment must necessarily be comprehensive.
As a rule, patients with congenital panniculitis, which occurs in chronic form, prescribe:
- Nonsteroidal anti-inflammatory drugs.
- Sharpening of knots with glucocorticosteroids.
In infiltrative and plaque form, administration of glucocorticosteroids and cytostatics is prescribed. To support the liver is shown taking heparoprotectors.
Physical treatment - phonophoresis, UHF, laser therapy is shown in all forms. Locally used ointments with corticosteroids.
With secondary fat granulomas, the main condition must be treated.
Treatment by folk methods
Additionally, phytotherapy can be used. For panniculite useful:
- Compresses from raw beets to a place of defeat.
- Compresses from Hawthorn Fermented Fruit.
- Compresses from Plantain Dusted Sheets.
It is useful to drink herbal teas cooked on the basis of Echinacea, hips, Eleutherococcus for general strengthening of the body.
Forecast and prevention of
Because the mechanism of development of primary panniculitis is unclear, there is no specific prevention of this disease. In order to prevent the secondary form of the disease, it is necessary to actively and persistently treat the underlying disease.
For chronic and subacute form of the disease, the prognosis is favorable. In the acute variant of the course of the disease - it is highly doubtful.