Breast Cancer Marker: What Does CA-19-9 Mean?
- 15 Jul 06:30
- Hemorrhoid Treatment
It's important to know! The only remedy for Gastritis and gastric ulcer , recommended by doctors! Read more. ..
SA 19 9 blood test - what does it mean and how to prepare for it? SA 19 9 is a carbohydrate oncomarker, a glycoprotein that determines the presence of a pancreatic cancer in humans. Considerthe main nuances of this analysis, the value of such a marker in identifying pathologies in the body.
- 1 What is SA-19-9?
- 2 Why do you need an examination?
- Marker Concentration Changes 4 Other Indicators
- 5 Tumor Marker for Colon Cancer and Liver Diseases
- 6 How do tests?
- 7 Additional researches
1 What is SA-19-9?
This is a special type of high molecular weight glycoprotein. It is a modified form of the antigen of Levis. Normally, in healthy cells of the pancreas, stomach, gall bladder, in the pulmonary tissue. Glycoprotein SA 19 9 is produced by cancerous tumor cells of the pancreas and much less frequently in the stomach.
Do you have gastritis?
GALINE SAVIN: "How to just cure gastritis at home at 1 month. Proven way - write a recipe. ..! "Read more & gt; & gt;
We recommend you to read
- Normal alkaline phosphatase in women
- Eggplant and enterobiasis
- What shows a biochemical blood test from the vein
Study of the concentration of this substance is extremely important in the diagnosis of pancreatic cancer. Thus, there is a marked increase in marker concentration in almost half of patients with suspected carcinoma. The level of CA 19 9 may vary depending on the stage of the cancer.
If CA 19 9 increases after surgery for pancreatic cancer, this may indicate a relapse or the appearance of metastasis. And if the body grows benign tumor, then increasing the number of markers is much less.
Antigen is not highly specific. Not recommended for screening.
- IMPORTANT TO KNOW! Gastritis? Ulcer? To prevent stomach ulcer from becoming cancerous, drink a glass. .. Read more & gt; & gt;
2 Why do you need an examination?
WE ARE RECOMMENDED!
For our prophylaxis and treatment of gastrointestinal tract our readers are advised Monastic tea. This unique device consists of 9 medicinal herbs useful for digestion, which not only complement but also enhance each other's actions. Monastic tea will not only eliminate all the symptoms of the DUS and digestive system, but will also permanently relieve the cause of its occurrence.
Doctors Opinion. .. "
Although the oncomarker is an indication of the presence of pancreatic carcinoma in the body, it does not indicate the presence of the disease at an early stage. So it is advisable to conduct such a study to control the effectiveness of anticancer treatment.
It is worth remembering that the marker SA 19 9 is excreted primarily from the body with bile. So if a person is disturbed by secretion and outflow of bile, it immediately affects its content in the blood.
To determine if a person has a dangerous disease, an analysis on this marker is required. You do not need to give up such a survey.
Monitoring the amount of pancreas should be done according to the following indications:
- preclinical examination;
- to determine the nature of the course of the disease of the pancreas and other organs of the gastrointestinal tract;
- patient tracking to exclude possible relapse of stomach cancer;
- tumor of the large intestine;
- stomach formation in the gallbladder;
- liver cirrhosis;
- cystic fibrosis;
- inflammatory pathology of the gastrointestinal tract.
3 Change in
marker concentration ADVICE FROM THE MAIN GASTOROTENEROLOGY
How to deal quickly with Ulcers and Gastritis, read interviews with the head of the GKT RAS Institute, Sergei Viktorovich Korotov. Read the interview & gt; & gt;
If the patient shows a concentration of CA 19 9 to 500 OD per milliliter, then with 50% probability, he can be diagnosed with pathologies not associated with the malignant process:
- hepatitis( acute or chronic toxic,
- stomach in the gallbladder)
If the patient has such a marker of more than 500 units per ml of blood, then it may have the following pathologies:
- cancers of female genital organs - uterus, ovary - 70%cases;
- breast cancer( 70 percent of cases);
- liver cancer, sigmoid colon, stomach, gall bladder - in 90% of cases;
- pancreatic cancer - always
Note that normal in pancreatic, gall bladder, liver cells,in the blood of the lungs is an acceptable number of tokagOncomarker - 10 to 37 units per ml of blood. Tomancers of high levels of pancreas always indicate malignant pathology
4 Other indicators of
The low values of such an antigen( its reference values - from 0 to 34 units per ml) indicate thatA person is healthy and has a low risk of developing a tumor. However, if the patient has a normal marker concentration, this does not mean that he does not have a malignant process. It happens when it has already begun, and the marker level has not yet managed to rise.
In any case, a person must remember that the higher the amount of antigen Sa 19 9, the lower the stage of cancer. The highest numbers of such markers occur in the case of metastasis.
You should also pay attention to the following remarks:
Some representatives of the Caucasian nationalities do not even produce such a marker even in the presence of a malignant process.
The accuracy of the analysis in terms of diagnosis is significantly increased with the simultaneous conducting of analyzes on REA, CA 242, CA 72-4 and on the overall indicator of bilirubin.
5 Oncomarker for colon cancer and liver diseases
- is indicated for differential diagnosis of carcinoma( when it is necessary, for example, to distinguish colon cancer from other forms of cancer);
- helps track the body's response to therapy;
- helps to detect relapses and metastases in the large intestine.
At present, there is not enough clinical data to allow the use of this oncomarker to determine the presence of a cancerous colon cancer patient. In all these cases, the test CA 19 9 is shown as an additional diagnostic measure.
This analysis is often used for differential diagnosis of liver and biliary tract diseases. Allows differentiation of cancerous formations and metastases in the pancreas with similar formations in the liver, gallbladder, bile ducts, etc.
The high diagnostic value of this test is explained, first of all, by the fact that this oncomarker is excreted in large quantities with bile. And if the body violates the conditions for outflow of bile, then in the blood immediately increases significantly marker indicators.
To enhance the diagnostic accuracy of the SA19 9 marker, 9 patients are additionally assigned a biochemical assay for gamma-glutamyltransferase and alkaline phosphatase. Determination of their activity allows us to judge the presence of a patient's severe liver disease, including malignant.
6 How do you test?
Blood from the vein is required for this test. It is taken from the patient in the usual way. The medical staff monitors the implementation of all precautionary measures for this test. Patient before taking blood should not feel nervous overload, engage in heavy physical work, burn, etc.
Preparation for taking blood from the vein is standard. A few hours before the procedure, you must refuse to eat. In addition, blood sampling is carried out on condition that the medication is discontinued. If this is not possible, then the patient must be alerted to the doctor.
A day before taking blood from the vein, the patient must prepare and follow a special diet. It is necessary to restrict, and even better, to exclude from the diet fried, greasy, smoked. Naturally, it is necessary to completely remove in any form alcohol.
7 Additional studies
Analysis of the SA19 9 marker, as well as other cancer markers, does not provide 100% accuracy. Therefore, in order to increase the accuracy of the diagnosis, additional examinations are necessary:
Thus, the analysis of CA 19 9 is an accurate diagnostic measure that allows determining the degree of progression of malignant pancreatic disease.
When conducting additional diagnostic measures, the doctor can make an accurate diagnosis and appoint the necessary treatment in each particular case.