Panadol helps with headaches
- 02 Jul 19:30
- Action mechanism
- Testimonials How to take Panadol
- Side effects and contraindications
- Admission during pregnancy and lactation
- Symptoms of overdose
- Price, reviews and conditions of departure from the pharmacy
Panadol is a drug that belongs to the group of analgesics andantipyretics, that is, it has 2 main effects: anesthetic and antipyretic. The active ingredient of Panadol is well known to all paracetamol.
The drug is produced mainly in oral forms( conventional and effervescent tablets, capsules).For children, the medicine exists in the form of syrups and suppositories. The dose of one adult pill is 500 mg. There is also Panadol Extract, which additionally contains caffeine. Available in cardboard boxes for 12 pieces in a blister.
Produces these drugs by the pharmaceutical company GlaxoSmithKline( Ireland).
Mechanism of action
The active ingredient of Panadol, paracetamol, belongs to nonselective NSAIDs. Paracetamol has a potent antipyretic, moderate analgesic and minimal anti-inflammatory effect.
The principle of work is related to the blockage of the enzyme, which inhibits the synthesis of prostaglandins( the main substances causing pain, inflammation and temperature rise).It is important to note that paracetamol, in addition to peripheral action, has a central. Therefore, it is used even in combination with narcotic analgesics to treat pain in cancer practice.
Drugs are well absorbed into the systemic blood flow from the gastrointestinal tract. It begins to act in 20 minutes. The maximum effect is observed after 40-120 minutes after taking the tablet. Metabolism of paracetamol occurs in the liver, which should be taken into account when prescribing medicines to people with chronic diseases of this organ, as well as with long-term use of the drug( periodic monitoring of liver function).
Testimony Most often, Panadol is used for headache and relief of fever. Medications quickly and reliably eliminate cephalalgia, regardless of the cause. The drug is effective even with migraines. It also works perfectly with the symptoms of influenza and other respiratory diseases( relieves muscle pain, headache, and fever).
Due to analgesic and antipyretic effect, Panadol helps in the following cases:
- primary and secondary types of headaches, migraines;
- pain joint syndrome;
- periodic pain in women;
- symptomatic treatment of influenza and ARI.
How to Take Panadol
Medications taken internally, no need to shred or chew. It takes a lot of fluid to burn. Spread tablets( Panadol Soblub) pre-dissolve in cold boiled water.
One-time and course dose is determined by a specialist for each individual individually. Recommended doses for children aged twelve and up to adults are 0.5-1 g( 1-2 pills) per serving. The number of receptions 3-4 times a day. The maximum amount per day should not exceed 4 grams, that is, 8 pills.
For children aged 6 to 12 years it is fashionable to use once every 250-500 mg of Panadol, the number of receptions is 3-4 times a day. The maximum amount of medicine for them should not exceed 2 grams per day.
You can not drink Panadol for more than 7 days, use the medicine on a hungry stomach. It is also important to consider that persons with pathology of the liver and kidneys need correction of doses to the lower side.
Side Effects and Contraindications
The drug is contraindicated:
- is an allergy to paracetamol or other additional pill components;
- chronic liver and kidney disease that caused these organs to fail;
- jaundice unclear genesis;
- genetic deficiency of the enzyme G-6-FDH;
- diseases of the blood system, in particular anemia and leukopenia syndrome;
- to people suffering from chronic alcoholism due to harmful effects on the liver.
. The drug is usually well tolerated by patients, but with the use of Panadol, the following side effects may develop:
- abdominal pain, nausea and vomiting;
- increased liver enzyme concentration;
- suppression of the hematopoiesis with the development of anemia, leukopenia, thrombocytopenia, agranulocytosis;
- development of a condition such as methemoglobinemia;
- various hypersensitivity reactions( skin rash, itching, swelling, anaphylaxis);
- hypoglycemia( a decrease in glucose concentration), which should be taken into account in patients with diabetes;
- development of toxic hepatitis or nephritis.
Admission during pregnancy and lactation
Paracetamol is the only drug that is authorized for use in patients with fever and headache in pregnant women, regardless of the term. According to the classification of the safety of drugs during pregnancy, he was assigned the category of Art.that is, it is a relatively safe drug, all animal studies( as similar studies in pregnant women are forbidden) have shown no adverse effects on the fetus. And all observations of paracetamol in pregnant women did not reveal an increased risk for the baby and the mother compared with the population.
The only thing to consider is the dose, it is half the adult, that is, one-time is 250-500 mg, the maximum daily dose is 2 g.
Panadol can also be used in nursing mothersin adult doses. The drug comes in breast milk, but after 4-5 hours it is excreted from the body. Therefore, after taking the pill, the baby should be fed after 4-5 hours. Thus, the medicine does not get into the baby's body.
Symptoms of overdose
May occur with a significant excess of these doses. This leads to the development of severe liver damage, abdominal pain, nausea, vomiting. It may occur hypoglycemic coma, bleeding of different localization.
The first aid consists in gastric lavage, absorption of sorbents. Specific antidote is acetylcysteine, which is prescribed in the first day after poisoning.
Price, reviews and conditions of departure from the pharmacy
The average price of Panadol( 12 tablets of 500 mg) is 50-100 rubles. The drug is included in the over-the-counter group and is released in pharmacies freely.
Video about the danger of overdose of paracetamol( Panadola):
Watch this video on YouTube
"Even from youth, I suffer from migraine headaches. As a rule, I accept tsitramon, nurofen. The last assault happened to me at work, there were no pills at hand. I got to the pharmacy, the pharmacist advised to try Panadol Extra( in it paracetamol and caffeine).The headache was removed by hand after the first pill. Now, I always carry a miracle cure in my handbag with it. "
" got acquainted with Panadol drugs on the advice of a girlfriend. Once, I fell ill, but could not afford to lie down, since the nose was a regular winter session exam. Braided Panadol 1 tablet 3 times a day. Immediately after the first, the temperature was normalized, the head cleared up, which allowed not block the session. "