Lupus of newborns - causes, symptoms, treatment, photos
- 21 Jun 23:30
- Disease Of The Skin
Lupus is a chronic inflammatory disease of autoimmune nature.
The immune system normally protects the body from the action of bacteria, viruses and other microorganisms. But sometimes it crashes, and the cells of the immune system begin to perceive their owntissues of the body as alien. As a result, the disease develops, which belongs to the category of autoimmune diseases. In such diseases, many organs and systems of the body can be affected. So, with systemic lupus erythematosus, skin, joints, kidneys, blood cells, heart, lungs, etc.
Lupus is a chronic disease that affects mostly young women. Unfortunately, it was not invented a remedy that could cure lupus, however, competently chosen treatment allows you to live a virtually normal life. Pregnancy in women with lupus erythematosus is not excluded, despite the fact that pregnant women with such a diagnosis are classified as "high risk".
Lupus can pass through the placental barrier, so about 3% of children born to mothers, sick of lupus, develops a specific syndrome - lupus of newborns.
- 1 Causes of
- 2 Pregnancy
- 3 Clinical picture of
- diagnostic methods 5
- treatment 6 Forecast and prevention of
- 7 Photo
development The cause of neonatal lupus development is fully understood. The disease develops through the placement of certain antibodies that are present in the mother's blood.
But the reasons that lead to the development of systemic or diskoid lupus are still not revealed. Although researchers have been able to identify factors that increase the risk of developing this serious autoimmune disease:
- . Rational factor: Lupus is affected by all races, however, cases of disease among Negroids, Hispanics and Asians are more frequent.
- Sexual factor. Women are ill more often than men. Neonatal lupus, also, is more common in girls than in boys.
- Age Factor. Lactation of newborns develops immediately after birth, or in the first weeks of life. Systemic or discoid lupus erythematosus can develop at any age, but more often this disease is diagnosed in the young.
- Solar Radiation. Ultraviolet can provoke exacerbation of the disease, especially its skin manifestations.
Since lupus is more likely to be infected by young women, the issue of preserving pregnancy and reducing the risk of developing newborn lupus is relevant.
Earlier, the issue of preserving pregnancy in patients with lupus of women did not stand. Patients were advised to carefully prevent, and in the event of pregnancy - an artificial abortion. Currently, this provision has been revised. It is also very important to know how red lupus is transmitted, which can provoke its development.
Approximately half of the cases, pregnancy in the background of lupus is allowed by the birth of a healthy child in a timely manner. About 25% of sick women give birth prematurely, however, the child appears to the world viable. And only in 25% of cases, the pregnancy in the patient ends with miscarriage and death of the child.
Birth cases with signs of neonatal lupus are fairly rare, and only 2-3% of children born to sick mothers have symptoms. However, if a woman already has a baby who has suffered a lupus uterus, the probability of having children with this disease in subsequent pregnancies is significantly increased.
Clinical picture of
Symptoms of neonatal lupus include skin lesions, cytopenia, myocarditis, pericardium and hepatolialial syndrome. All these manifestations, as a rule, have a transient nature, that is, they are temporary and pass through 6-9 months, until the destruction of antibodies derived from the mother.
Skin manifestations - this is the most common symptom of neonatal lupus. Skin rash can be detected on the first days after birth or during the first month. Somewhat less rarely the first skin symptoms of neonatal lupus appear in 2-3 months.
On the skin of the face, head, shoulders a rash appears in the form of polycyclic or ring-shaped erythema. The rash, as a rule, has clear boundaries, along the edges of the foci there is peeling of the skin. In a histological examination, a typical lupus erythematosus affects the skin. By the age of 6-9 months skin rashes in lupus neonatal pass without trace, relapses during a lifetime is not observed.
The permanent symptoms of lupus erythematosus include defeat of the cardiovascular system, which are observed in 35-50% of ill children. It is a defeat of the congenital atrioventricular block in the presence or absence of congenital heart disease. Serious heart defects in lupus neonatal are noted in boys in 1.6 times more often than in girls.
Violation of atrioventricular conduction may be complete or partial, they are often noted in combination with non-transfusion of arterial duct and defects of interventricular septum.
Congenital atrioventricular blockade is the most serious manifestation of neonatal lupus. When combined with heart disease, it can lead to the death of a child in the period of newborn birth. In the absence of concomitant defects in the heart, the survival rate of patients is quite high( 95%).
Another serious symptom of lupus neonatal, however, as well as other common skin diseases( eg, Paniculitis Weber-Chryschenko, psoriasis, sarcoidosis, etc.) - liver damage, Art. Patients with children often detect hepatosplenomegaly and cholestasis. However, these symptoms, as a rule, pass, and, like skin manifestations, disappear during the year.
Liver tumors in patients with neonatal lupus rarely seen. And this is, in the main, education of a benign nature. Normally, no external manifestations of the tumor in the liver are given, they are detected during routine inspections. The most common neoplasms in the liver in patients with neonatal lupus are hemangiomas or hemangioendotheliomas, that is, vascular tumors, as well as various vascular pathologies.
Women with red lupus erythematosus should carefully plan their pregnancy. Why, you will learn from this article. It is important that the period of pregnancy falls on the remission of the disease, this will reduce the risk of complications for both the mother and the future child.
It is necessary to register as soon as possible during pregnancy and to remain under the supervision of physicians. It is important to regularly monitor the growth and development of the fetus using ultrasound and other research methods.
Patients with lupus erythematosus, especially lupus in a subacute form, women should undergo a study on the presence of specific antibodies in the blood in the early stages of pregnancy.
The timely detection of signs of developing a heart defect in the fetus will allow you to find the most beneficial delivery tactics. When the fetal signs of a bradycardia of a pregnant woman should be sent to abdominal ultrasound and non-stress fetal tests. After 28 weeks, fetal echocardiography is indicated.
Diagnosis of neonatal lupus erythrocytes in already born children consists in conducting of physical, instrumental and laboratory researches. Physical studies consist in studying the appearance of rash. Laboratory research is the analysis of the content of blood in specific antibodies.
A series of instrumental studies - ultrasound, ECG, echocardiography and others - are performed to detect lesion of the heart and liver.
The treatment method for neonatal lupus is based on the severity of symptoms. When acute course of the disease is shown hospitalization. To reduce the skin appearance of lupus neonates use 1% hydrokorticosteroid ointment.
Symptomatic treatment is indicated for detecting cardiac violations. At detection of congenital defects an operative treatment is carried out.
Forecast and prevention of
The prognosis for lupus uterus is uncertain and depends on the degree of damage to the cardiovascular system. Skin manifestations in neonatal lupus arise, as a rule, without a trace, recurrence does not occur.
Prevention of newborn lupus is to carefully prepare for pregnancy and adhere to all doctor's recommendations in the process of carrying. Women who have lupus erythematosus, as well as women whose blood has been found to have specific antibodies in the absence of clinical manifestations of the disease, is recommended to be screened before pregnancy.
In the process of bearing the fetus, it is recommended:
- Protect skin from ultraviolet radiation. Sun rays can trigger an exacerbation of the chronic process and increase the risk of having a baby from a neonatal lupus.
- Follow the doctor's recommendations carefully. Pregnant, ill lupus, should pay particular attention to the recommendations given to them by the doctor. In no case can you take any drugs yourself, based on the recommendations of friends.
- It is important to adhere to a balanced diet and to rest more often. These recommendations can be attributed to all pregnant women, and women who are ill lupus need to follow the diet and diet with particular attention.
- You have to quit smoking. Smoking has a negative effect on the course of pregnancy and increases the risk of developmental heart disease in the future baby.
- You can not refuse treatment prescribed by your doctor. Some pregnant women believe that at the time of pregnancy should refrain from taking all medicines. This idea is true for completely healthy women, but if the doctor prescribes treatment, then it is necessary to undergo a course, as refusal of treatment can lead to the development of complications, both in the fetus and in the mother.