Ointment Protopic: Instructions for use
- 08 Sep 05:15
- Hemorrhoid Treatment
Protopic - an ointment for external use, prescribed by dermatologists for the treatment of atopic dermatitis. The pharmaceutical manufacturer is the Netherlands pharmaceutical company "Aslellas Pharma Europe V.V.".With topical application, Protopik provides skin-affected skin dermatitiswith anti-inflammatory effects and promotes rapid healing. It is easy to use, but it has a lot of contraindications and unwanted actions, and therefore should be appointed only by a qualified specialist.
1 Information on the composition, indications and contraindications of
The active component of Protopics is tacrolimus, an immunosuppressant that belongs to a class of natural macrolides. In the preparation, it is presented under the guise of creatine in two doses - 0.03% and 0.1%.The auxiliary components of the ointment are propylene carbonate, white beeswax and paraffin in the solid, soft and liquid state.
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Protopic is made in the form of white or light yellow cream of homogeneous consistency packed in 10, 30 and 60 m in aluminum tubes. Each tub is placed in cardboard packaging and is provided with an instruction containing the information on the composition of drugs, its properties and features of application.
Indications for use Protopics is the treatment of moderate to severe atopic dermatitis. It is advisable to prescribe ointment in cases where the use of other therapeutic methods did not make the patient noticeable relief. Protopic 0.1% and 0.03% are used in the treatment of adolescents over 16 years of age and adults. In pediatric practice it is allowed to use a cream only with a dosage of active substance 0,03%.
Ointment can use Protopic not for all categories of patients. Contraindications to the use of the product are:
- sensitivity of the body of the patient to the components that are part of it;
- Individual intolerance to macrolides;
- child bearing;
- less than 2 years of age( for Proto-Pacific 0.03%);
- is less than 16 years of age( for a 0.1% dose cream);
- diseases, accompanied by severe skin lesions( lamellar ichthyosis, exfoliative erythroderma, Netterton's syndrome).
Although Protopic is applied externally, tacrolimus is partly metabolised by the liver. For this reason, the appointment of an ointment for persons suffering from hepatic insufficiency should be marginally precise and only if other treatments are not possible. Exposure to large areas of the skin should be done only in case of extreme need and under the control of a doctor.
2 Use, Side Effects, and Overdose
Cream Protopic application instructions recommends smearing the foci of a defeat with a thin layer. It is used in the treatment of dermatitis, localized on the body and face. The application of the drug to the mucous membranes is strictly contraindicated. Also, do not use the product on sites that are under a sealed bandage and adhere tightly to the body of clothing. The ointment can remove inflammation of the skin affected by atopic dermatitis, eliminating itchy and dry skin characteristic of this disease.
The use of Protopics should be carried out in accordance with a specialist treatment scheme. It is intolerable to adjust it yourself, increase or decrease the amount of application of the cream on the skin, as well as prolong or reduce the duration of the course. Strict adherence to medical recommendations will allow the patient to achieve complete relief from the manifestations of atypical dermatitis without significant harm to health.
People who the doctor appointed Protopic often complains about the onset of the use of local adverse reactions in the form of redness of the skin, onset of itching, rash and painful sensations. The described symptoms usually occur at the beginning of therapy and go on their own during the first days of treatment. If they are moderately expressed, then it is not necessary to cancel the drug. In the event of severe irritation at the site of application of the ointment to the patient, you should refuse to use it and seek medical advice, which will replace it with another drug.
In addition to local reactions, the device can cause the following side effects:
- local skin infections, including folliculitis, herpetiform eczema, herpes simplex, Kaposi's varioformiform pustulosis;
- intolerance to alcoholic beverages( reddening of the face arising from the use of alcohol);
- sensation of heat at the place of contact of the preparation with the skin;
There is no information on overdose with ointment at local time. In case of accidental ingestion of the patient, it is necessary to consult a doctor as soon as possible. The manual does not recommend to rinse the stomach yourself, provoking an emetic reflex by artificial means, as the auxiliary components of the ointment with the help of these actions can not be removed from the body.
3 Features of the use of the product, storage requirements and analogues
Present as part of the Protopic tacrolimus, at local application, is not biotransformed in the skin tissues, therefore its interaction with other medicinal products is unlikely. But people who are forced to apply a cream on large surfaces of the skin or suffer from eritrodermia, it should not be completely excluded. For this reason, co-administration of CYP3A4 inhibitors should be avoided.
During treatment with Protopics, vaccination should be discontinued.
It should be taken either before the start of therapy, after a crescent after its completion. Administration of an attenuated patient in a patient's body( a live vaccine should be performed not earlier than 1 month after discontinuation of the cream.)
During the treatment period the patient is prohibited from being exposed to direct sunlight for a long time, attending a solarium, and receiving health treatments in which ultraviolet radiation is usedProtopic ointment can not be applied to areas of the skin with malignant neoplasms. Within 2 hours after using the medicine, it is not recommended for the patient to treat the skin with any
Use the cleansing fingers on the affected skin with clean fingers After the procedure, the hands should be washed in warm water and soap So that the medicine does not get into the digestive tract of the patient, during its use it is strictly forbidden to eat, usedrink or smoke. Only ensure that the ointment does not get into the mucous membranes or eyes. If this can not be avoided, it should be thoroughly washed away from the affected area with plenty of cool water.
Protoxic cream can be purchased at any pharmacy in the presence of a prescribed recipe. Its expiration date is 36 months from the date of manufacture. Store the ointment in a dark and dry place at room temperature.
At the pharmacy today you can find many drugs with an action similar to Protopik. These include Proof, Advancraph, Vingraf, Tacrolimus, Elidel, Flades, Flucinar, Lorinden, Acriderm, etc. These drugs are used to treat dermatitis in children and adults, but have different composition and peculiarities of application. To accept them, as well as Protopik, should be only on the recommendation of the attending specialist.