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Composition of the drug Mezim Forte in pills

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With complete absence or insufficient digestive enzymes, there is discomfort and pain in the epigastric region. To alleviate

, unpleasant symptoms are prescribed enzymes that contribute to better digestion. Mezim Forte is considered to be the leading medicine in this area for efficiency and affordability.


  • 1 When is the tool assigned?
  • 2 Unlike the standard Mezim and Mezim Fort
  • 3 Dosage and treatment regimen
  • 4 Contraindications and important features of
  • 5 Pregnancy and lactation period
  • 6 Interaction with other medicines

1 When is the remedy used?

Mezim and Mezim Forte are the most affordable for purchasing pancreatin-based preparations with different enzyme activity. Effectively used in a number of diseases of the gastrointestinal tract, as well as with temporary indications, which include:

  • preparation for contrast or ultrasound examination of the abdominal cavity;
  • is a one-time overeating or use of heavy food for digestion even under the normal functioning of the SLE;
  • disorders of the gastrointestinal tract and intestinal microflora after antibiotic therapy or surgical interventions.

For long-term treatment of patients, enzyme medications are prescribed in diseases that affect the secretory function of the stomach, pancreas, gall bladder, liver and intestines. These pathologies include various inflammatory processes and dystrophic changes in organs.

The need, duration and frequency of admission is determined by the presence of symptoms such as flatulence, abdominal distension, digestive disorders, nausea, feeling full of stomach, weight and pain after eating.

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2 Unlike the standard Mezim and Mezim Forte


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Doctors Opinion. .. "

The mesim contains pancreatin in the amount of 220-293 mg per 1 tablet, Mesim Forte contains approximately 138 mg of pancreatin. The basis for choosing one of these medications is the convenience of using - if the patient has a sufficiently small dose of the active substance, then it would be advisable to purchase a drug marked "Forte".In more complex cases requiring more enzymes, the standard form of release is better.

Enzyme activity, OD Ph. Eur
Standard release

Additional component - simethicone - helps to neutralize the increased gas formation, and auxiliary substances do not cause allergic reactions in patients.

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Composition of the drug Mezim Forte in pills

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3 Dosage and Therapy Scheme


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The dosage depends on the indications before appointment, the age of the patient, and the accompanying symptomatology. The gold standard for treatment with Mesim Forte is the use of 1-2 tablets before each meal. The tablets are streamlined and easily swallowed with water.

If the standard dose was insufficient, then it is possible to prescribe a few more pills, but already during the meal. Children under the age of 18 are appointed in a minimum amount. The maximum daily dose should not exceed 20,000 lipase units per kilogram of body;for children - up to 1000 units of lipase per kg, but with each meal.

The duration of application can range from single ingestion of tablets up to several years, especially with substitution therapy.

Composition of the drug Mezim Forte in pills

4 Contraindications and important features of

Despite the exceptional enzyme activity, the drug has a contraindication and is not prescribed:

  • in acute pancreatitis;the appointment of pancreatin is possible only with the compensation of the condition and the transition of the inflammatory process to the chronic form;
  • at the age of three years due to the impossibility of correct selection of dosage of this form of release;
  • with individual intolerance to any of the components, including glucose-galactose malabsorption.

Composition of the drug Mezim Forte in pills

5 Pregnancy and lactation period

Enzymes included in the drug do not have embryotoxic, teratogenic, or stimulates the birth effects of the effect. In this regard, the remedy is considered safe for use in obstetrics on the testimony. It should be borne in mind that enzyme preparations can reduce the absorption of folic acid, so during the treatment with amylase, lipase and protease, it is necessary to increase the dose of folate intake, especially in the first trimester.

Composition of the drug Mezim Forte in pills

6 Interaction with other drugs

Iron-containing drugs, hypoglycemic drugs are absorbed in parallel treatment with enzymes. Antacids with calcium carbonate or magnesium hydroxide reduce the effectiveness of enzymes.

No effect on the psychomotor reaction was noted. When prolonged treatment with this drug is recommended to monitor the level of uric acid in the blood plasma. In this case, as well as signs of overdose, symptomatic treatment with withdrawal of the drug and subsequent dose adjustment are performed.

The extract of the pancreatic secretion, contained in Mezime, is a very effective remedy that complements its deficiency and helps to improve digestion. Proper selection of doses with the exception of contraindications to admission eliminates unpleasant symptoms in the human's digestive tract and provides medical support in the complex therapy of chronic, compensated pancreatitis, cystic fibrosis and other inflammatory, infectious and dystrophic diseases of the abdominal cavity.