Helps Vazobrow with migraines and how
- 05 Sep 02:30
- mechanism of action
- How to take Vazobral
- side effects and contraindications
- take during pregnancy and lactation
- Symptoms of overdose
- Price, feedback and Conditions of supply of pharmacies
Vazobral - a comprehensive drug that was created toimprovementblood circulation in the vessels of the brain. During the clinical studies of the drug was proved its good effectiveness in the prevention of migraines, so Vazobravel used in migraines quite often.
The medicines include:
- dihydroergocritin( alpha adrenergic blocker),
Vazobar is available in two dosage forms: a tablet solution for internal intake. Tablets can be found in 2 dosing options:
- 2 mg dihydroergocroptin and 20 mg caffeine,
- 4 mg dihydroergocroptin and 40 mg caffeine.
In one cardboard box there are 1 or 3 blisters for 10 pieces.
The solution is available in a single dose in 50 ml vials of 1 ml containing 1 mg of dihydroergocroptin and 10 mg of caffeine. In the package you can find a convenient pipette for dosing, which can be collected in 2 ml of solution.
Manufacturer Vazobrava is a French pharmaceutical company CHIESI S.A.
. Mechanism of action
Dihydroergocritin is a blocker of adrenergic receptors of smooth muscle cells in the blood vessels. Also, this substance activates serotonin and dopamine receptors, promotes the reduction of aggregation of platelet and erythrocytic cells, reduces the throughput of the membranes of the blood capillaries, increases the area of vascular capacity. As a result of this action of the drug, blood flow improves in the nervous tissue, the nervous cells become resistant to hypoxia.
Caffeine has a psychostimulatory effect. It raises the intellectual and physical capacity of a person, reduces manifestations of asthenia and drowsiness, has a stimulating effect on the vascular and respiratory centers.
Due to such effects, the combination drug Vazobar shows good results of complex therapy of asthenic disorders, cerebrovascular disorders, with residual effects of cerebrovascular disorders, with diseases of the inner ear, Meniere's illness, with disturbances of peripheral circulation, mental degradation and memory impairment.
. Vazobar is also widely used in migraine attacks between attacks and helps to prevent new migraine headaches. As a rule, for this purpose, the drug is prescribed in patients with frequent attacks( 2 or more times per month).
Vazobar is indicated for the following pathological conditions and diseases:
- warning of migraine episodes;
- cerebral atherosclerosis and its consequences;
- chronic cerebrovascular failure;
- treatment of stroke effects;
- elimination of symptoms of internal ear and vestibular nerve pathology( head swirling, ear tension, disturbances with nausea attacks);
- fading mental and mnestic functions;
- Menier's disease;
- pathology of retina vessels with hypertension, diabetes;
- narrowing of the vessels of the lower extremities;
- varicose veins;
- Raynaud's syndrome;
- vegetative-vascular dystonia;
- to eliminate the symptoms associated with meteosensitivity.
The drug is well absorbed by the mucous membranes of the digestive tract, which is promoted by caffeine. The maximum concentration of the active substance in the blood is observed after 2 hours.
It is important to know that Vazobar can be used not only for the prevention of migraine attacks, but also for their treatment. Since the main active ingredient, dihydroergogryptin, is included in the group of alkaloids horns, which are considered to be drugs of choice for the elimination of migraine attacks.
How to take Vazobar
Preventive treatment with Vazobram is performed only with frequent and severe migraine episodes. The choice of dose, multiplicity and duration of admission is determined only by the doctor, based on the individual characteristics of the patient and the form of his illness, accompanying symptoms and pathologies.
The recommended scheme for the prevention of migraine: ½ - 1 tablet( 4/40 mg) or 2-4 ml solution twice a day. The therapeutic course is 3-4 months of continuous administration, after which the need for the continuation or withdrawal of the drug is determined.
It is better to take medicines while eating, drinking a small amount of liquid. The solution can be diluted 5-10 ml of water.
Take 1 tablet( 4/40 mg) or 4 ml of solution for relief of the attack. Thus, the earlier the treatment started, the better result. After the first dose, if it does not help, you can take this only in 2 hours, with only half a tablet( 2/20 mg) or 2 ml of solution. The daily dose should not exceed 10 mg of dihydroergocroptin.
Side Effects and Contraindications
Vazobar is not recommended for use in the following cases:
- Hypersensitivity to the main components of the drug or to the adjuvants of the tablet, solution;
- Pregnancy and Breastfeeding;
- child up to 18 years old.
pressure. Vazobrole treatment may have the following side effects:
- disruptions of falling asleep;
- arterial hypotension;
- pain in the epigastric region;
- heart disorders, including tachycardia;
- dizziness, headache, short-term arousal.
Basically all patients are well tolerated by Vazobrole, side effects develop in rare cases.
Admission during pregnancy and lactation
There is no data on how Vazrola's administration affects the fetus and the course of pregnancy, therefore the drug is contraindicated in pregnancy until the opposite is proven. If there is a need for its appointment, this should only be done by a qualified specialist after assessing the benefit / risk for the mother and the child.
Treatment With a lactation of nursing mothers leads to a reduction in the formation of breast milk. Therefore, the drug is not recommended for the appointment of this category of patients. In addition, there is no data on whether the drug penetrates breast milk and how it affects the baby.
Symptoms of overdose
Signs of overdose may occur if the maximum recommended dose of the drug( 10 mg of dihydroergocroptin) is exceeded. In such cases, patients complain of general weakness, low blood pressure, insomnia, palpitations, abdominal pain, nausea, dizziness, and headache. Only symptomatic treatment, specific antidote therapy does not exist.
Interactions: Care should be taken to monitor the condition of the patient treated with Vazobrole while taking the following medications:
- antihypertensive drugs( there is a risk of hypotension and even unconsciousness);
- hypnotics and sedatives( the effect of the latter is reduced due to the presence of caffeine in Vazobra);
- anti-parkinsonian medicines, in particular levodopa( increased risk of developing side effects such as abdominal pain, swelling, fever, cephalalgia, and impaired consciousness).
Price, reviews and conditions of departure from the pharmacy
The average packing price of Vazobrava( 30 tablets) is 950 rubles, a solution of 50 milliliters can be purchased for 550 rubles. The drug should be stored in dry and cool conditions, inaccessible to children. The shelf life of the tablets is 4 years from the time of release, and the solution for internal reception - 3 years. At the end of the specified period, the use of medicines is strictly prohibited.
Vazobar is part of a group of potent medicines, so a pharmacy can only be given at the doctor's prescription.
Video Transmission of Migraine Treatment:
Watch this video on YouTube
Reviews of WASBRAEL:
"For several years I have been suffering from migraine. Attacks have always been not very frequent 2-5 times in half a year. But after the pregnancy and the birth of a child, they began to torture me very often( 2-3 times a month).Unfortunately, I had to abandon breastfeeding, since I often had to take various anesthetic drugs that were not compatible with breastfeeding. Having failed this situation, I turned to the experienced neurologist for help. The doctor said that I often have attacks and I can not do the same pills for relief of pain, it is necessary to take preventive treatment. The specialist prescribed me the drug Vazobravel 1 tablet 2 times a day. The first month of admission was not changed. I already wanted to throw these medications, since they are not cheap, but noticed, the attack was not already two weeks. Reception I continued and did not regret. In the next 3 months, I had only 2 migraine attacks and then not very strong. Vazobul doctor has written to me for 6 months, after which it will be necessary to make a break. I hope that the pain will not come back. "
" After long and painful moves on doctors and a whole series of tests, my symptoms determined the diagnosis of vegetative-vascular dystonia with frequent sympathoadrenal crises. As the therapist explained, this is not at all scary, but my state of health speaks of another. The doctor prescribed me the drug Vazobar on a tablet twice a day. Two weeks later, the high blood pressure returned to normal, dizziness stopped and headache, as if I was born again. I have been receiving Vazobar for 3 months and I am very thankful to the doctor for advice. "
" I have been working as a neurologist for 15 years. Since the time when Vazobar appeared on sale, he did not badly promise himself in my practice. I prescribe this medication mainly to elderly patients with signs of vascular lesion of the brain. It eliminates dizziness, headache, noise and ringing in the ears, which significantly reduce the quality of life of such people. Recently, I started using Vazobar and for preventing migraine attacks in young women. So far the results are pleasing. "